CARCINOGENS, DNA DAMAGE AND CANCER RISK: MECHANISMS OF CHEMICAL CARCINOGENESIS

CARCINOGENS, DNA DAMAGE AND CANCER RISK: MECHANISMS OF CHEMICAL CARCINOGENESIS

CARCINOGENS, DNA DAMAGE AND CANCER RISK: MECHANISMS OF CHEMICAL CARCINOGENESIS

by: Miriam Christine Poirier (Author)

Publisher: World Scientific Publishing Co

Edition: 1st

Publication Date: 2019-01-13

Language: English

Print Length: 350 pages

ISBN-10: 9813237198

ISBN-13: 9789813237193

Book Description

As chemical exposures and cancer rates increase worldwide, there is a need for students, researchers, public health professionals, and physicians to understand the mechanisms connecting exposure with human cancer risk. This new book is an essential reference, as well as introduction to the field of chemical carcinogenesis, with particular focus on DNA damage as a critical link between exposure and disease, and emphasis on biomarkers associated with cancer risk in humans. In addition to DNA damage, related topics covered include metabolism of selected chemical carcinogens, exposure-induced epigenetic changes, cancer-associated mutations and reduction of DNA damage and cancer risk by chemoprevention. The book is designed to be a comprehensive guide to basic principles, a teaching tool for academics, and a map for the development of protective mechanisms to reduce human cancer risk. Readership: Undergraduate students, postgraduates and researchers in nuclear chemistry, pollution, biochemistry, biological chemistry and oncology.

Editorial Reviews

As chemical exposures and cancer rates increase worldwide, there is a need for students, researchers, public health professionals, and physicians to understand the mechanisms connecting exposure with human cancer risk. This new book is an essential reference, as well as introduction to the field of chemical carcinogenesis, with particular focus on DNA damage as a critical link between exposure and disease, and emphasis on biomarkers associated with cancer risk in humans. In addition to DNA damage, related topics covered include metabolism of selected chemical carcinogens, exposure-induced epigenetic changes, cancer-associated mutations and reduction of DNA damage and cancer risk by chemoprevention. The book is designed to be a comprehensive guide to basic principles, a teaching tool for academics, and a map for the development of protective mechanisms to reduce human cancer risk. Readership: Undergraduate students, postgraduates and researchers in nuclear chemistry, pollution, biochemistry, biological chemistry and oncology.

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