Translational Medicine and Drug Discovery Reprint Edition
Author(s): Bruce H. Littman MD (Editor), Rajesh Krishna PhD FCP
Publisher: Cambridge University Press
Publication Date: October 30, 2014
Edition: Reprint
Language: English
Print length: 384 pages
ISBN-10: 1107435943
ISBN-13: 9781107435940
Book Description
This book, edited by two innovative leaders in the field, focuses on the new discipline of translational medicine as it pertains to drug development within the pharmaceutical and biotechnology industry. Translational medicine seeks to translate biological and molecular knowledge of disease and how drugs work into innovative development strategies that reduce the cost and increase the speed of delivering new medicines for patients. This book outlines general strategies, biomarker development, imaging tools, translational human models, and examples of their application to real drug development. The latest thinking is presented by researchers from many of the world's leading drug development companies, including Pfizer, Merck, Eli Lilly, Abbott, and Novartis, as well as academic institutions and public-private partnerships that support translational research. This book is essential for anyone interested in translational medicine from a variety of backgrounds: university institutes, medical schools, pharmaceutical companies, and drug development researchers and decision-makers.
Editorial Reviews
Review
"This timely book provides an insightful, comprehensive compilation of contemporary issues related to the discipline of translational medicine, with particular application to early drug development... the editors appear to have accomplished their attention of providing biomedical researchers a condensed yet detailed reference... This reasonably priced book is particularly recommended for scientists new to the discipline." MF Paine, Clinical Pharmacology & Therapeutics
"This is an important book in a relatively new and growing field. Anyone engaged in advanced research designed to bring new drugs and biologics to market will find it valuable." Edward Tabor, Drug Information Journal
Book Description
This book focuses on the new discipline of translational medicine as it pertains to drug development within the pharmaceutical and biotechnology industry.
About the Author
Rajesh Krishna, PhD, FCP, is an area lead director in early stage development at Merck Research Laboratories. Dr Krishna is the editor of three books on new drug development besides publishing over 120 articles and oral/poster presentations. He has served as a section editor for the Journal of Clinical Pharmacology, associate editor for BMC Clinical Pharmacology and an editorial board member for BMC Medicine. He is a Fellow of the American College of Clinical Pharmacology and the American Association of Pharmaceutical Scientists, where he is the current Chair of the Clinical Pharmacology and Translational Research section. He is an affiliate member of the Institute of Translational Medicine and Therapeutics at the University of Pennsylvania.
Bruce Littman, MD, is the founder of Translational Medicine Associates, LLC, as well as former co-chair and current member of the Inflammation and Immunity Steering Committee of the Biomarker Consortium. Prior to starting his own company, Dr Littman was the Vice President and Global Head of Translation Medicine at Pfizer Inc. where he worked for nineteen years, first in experimental medicine and then translational medicine. He was also a faculty member of Virginia Commonwealth University School of Medicine for thirteen years. He is a Founding Fellow of the American College of Rheumatology, former President of the Virginia Society of Rheumatologists and a Fellow of the American College of Physicians.
Wow! eBook
