Transgenerational Toxicology in Caenorhabditis elegans

This book focuses on transgenerational toxicology using Caenorhabditis elegans as a model organism. C. elegans provides a powerful system for assessing toxic effects across generations because of its high sensitivity to environmental exposures and short life cycle. This book systematically presents current knowledge on the mechanisms underlying transgenerational toxicity, including toxicant translocation, biological barriers, intergenerational signaling, metabolic regulation, GPCR and nuclear hormone receptor pathways, and epigenetic control. It integrating protective responses and molecular regulatory networks, and offers readers a comprehensive framework for understanding and investigating transgenerational toxic effects in environmental and molecular toxicology research. This book serves as a valuable reference for researchers and graduate students in related areas of research.

Dr. Dayong Wang is a professor at the Medical School, Southeast University, China. He obtained his Ph.D. from Peking University in 2001 and completed his post-doctoral training at the University of Toronto from 2002 to 2004. His research focuses on toxicology and pathology using Caenorhabditis elegans as a model animal, fields in which he has published more than 340 research articles. Dr. Wang has published five books with Springer, all of which are centered on the toxicology in Caenorhabditis elegans.