
Toxicological Risk Assessment of Chemicals: A Practical Guide
Author(s): Elsa Nielsen (Author), Grete Ostergaard (Author), John Christian Larsen (Author)
- Publisher: CRC Press
- Publication Date: 21 Feb. 2008
- Edition: 1st
- Language: English
- Print length: 446 pages
- ISBN-10: 0849372658
- ISBN-13: 9780849372650
Book Description
Unlike many existing books on toxicology that cover either toxicity of a particular substance or toxicity of chemicals on particular organ systems, Toxicological Risk Assessment of Chemicals: A Practical Guide lays out the principle activities of conducting a toxicological risk assessment, including international approaches and methods for the risk assessment of chemical substances. It illustrates each step in the process: hazard identification, a dose response assessment, and exposure assessment. The book also summarizes the basic concepts of interaction of chemicals in mixtures and discusses various approaches to testing such mixtures.
Features:
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- Addresses standards from all international regulatory agencies
- Presents the steps in risk assessment, including hazard identification, exposure assessment, and risk characterization
- Covers the assessment of multiple chemical exposures or chemical mixtures
- Contains data from both human and animal studies
- Explains the linearized multi-stage mathematical model widely used by the US EPA for characterizing
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