Stress, Catecholamines, and Cardiovascular Disease

Stress, Catecholamines, and Cardiovascular Disease book cover

Stress, Catecholamines, and Cardiovascular Disease

Author(s): David S. Goldstein (Author)

  • Publisher: OUP USA
  • Publication Date: 27 April 1995
  • Language: English
  • Print length: 562 pages
  • ISBN-10: 0195065387
  • ISBN-13: 9780195065381

Book Description

Stress is an integral part of life. But what is it, how does it affect the body economy, and what role does it play in acute and chronic manifestations of cardiovascular diseases? This book provides a comprehensive analysis of these issues, from the basis of a new homeostatic theory of stress and distress. This theory is then used to explain the important role of catecholamines and other effector systems in maintaining the internal environment during periods of stress. The presentation summarizes difficult and complex literature about central neural mechanisms participating in sympathoadrenal reponses to stress and analyses theories about the roles of catecholamines in the brain. Clinical methods to assess sympathoadrenal activity are described, including the latest tracer-kinetic and nuclear scanning techniques. The possibly pathophysiologic effects of derangements of catecholaminergic function in cardiovascular diseases receive particular attention. Separating fact from opinion, the book considers objectively several prevalent and controversial theories linking stress and cardiovascular disease. As such, it is a challenging and thought-provoking reference, indispensable for all cardiologists, physiologists, neurologists, and psychologists.

Editorial Reviews

About the Author

David S. Goldstein, M.D., Ph.D. is a senior investigator at the National Institutes of Health and is the Chief of the Clinical Neurochemistry Section in the Clinical Neuroscience Branch of the National Institute of Neurological Disorders and Stroke.

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