Wow! eBook
Statistics and Informatics in Molecular Cancer Research
Author(s): Carsten Wiuf (Editor), Claus L. Andersen
- Publisher: OUP Oxford
- Publication Date: 18 Jun. 2009
- Edition: Illustrated
- Language: English
- Print length: 218 pages
- ISBN-10: 0199532877
- ISBN-13: 9780199532872
Book Description
Aimed at graduates and researchers, this book discusses novel advances in informatics and statistics in molecular cancer research. Through eight chapters from carefully chosen experts it brings the reader up to date with specific topics in cancer research, how the topics give rise to development of new informatics and statistics tools, and how the tools can be applied. The focus of the book is to give the reader an understanding of key concepts and tools, rather than focusing on technical issues.
A main theme is the extensive use of array technologies in modern cancer research – gene expression and exon arrays, SNP and copy number arrays, and methylation arrays – to derive quantitative and qualitative statements about cancer, its progression and aetiology, and to understand how these technologies on one hand allow us learn about cancer tissue as a complex system and on the other hand allow us to pinpoint key genes and events as crucial for the development of the disease.
Editorial Reviews
About the Author
Claus L. Andersen earned his PhD in cancer biology from the University of Aarhus in 2002. In 2002 he became an assistant professor at the University of Aarhus and later in 2005 an associated professor. Today he is heading the colorectal cancer research group at the Molecular Diagnostic Laboratory, Aarhus University Hospital.
Both have worked on informatics approaches to the analysis of molecular cancer data and have practical as well as theoretical experience with development of bioinformatics and statistical methods for analysis of molecular data.
