Wow! eBook
Selected Papers of Frederick Sanger with Commentaries: 1
Author(s): Margaret Dowding (Editor), Frederick Sanger
- Publisher: World Scientific Publishing Co Pte Ltd
- Publication Date: 1 Oct. 1996
- Language: English
- Print length: 678 pages
- ISBN-10: 9810224303
- ISBN-13: 9789810224301
Book Description
This important volume is mainly concerned with the development of methods for “sequencing” ― that is, determination of the order of the amino acids in proteins and of nucleotides in RNA and DNA. In 1943 the position of only one amino acid in a protein (insulin) was known, and Sanger’s first paper resulted in finding a second amino acid. In his final paper in 1982 he describes the determination of a DNA sequence of 48,502 nucleotides. The papers describe the steady improvements in techniques, and exciting biological results revealed by the sequences.
