The Resolution Revolution: Recent Advances In cryoEM: Volume 579
Author(s): R. A. Crowther
Publisher: Academic Press
Publication Date: 25 Aug. 2016
Language: English
Print length: 486 pages
ISBN-10: 0128053828
ISBN-13: 9780128053829
Book Description
cryoEM, a new volume in the Methods in Enzymology series, continues the legacy of this premier serial with quality chapters authored by leaders in the field. This volume covers research methods and new developments in recording images, the creation, evaluation and validation of 3D maps from the images, model building into maps and refinement of the resulting atomic structures, and applications of essentially single particle methods to helical structures and to sub-tomogram averaging.
Editorial Reviews
Review
Praise for the Series: “Should be on the shelves of all libraries in the world as a whole collection.” –Chemistry in Industry “The work most often consulted in the lab.” –Enzymologia “The Methods in Enzymology series represents the gold-standard.” –Neuroscience
Review
This new volume in the Methods in Enzymology series continues the legacy of this premier serial with quality chapters authored by leaders in the field, with this volume bringing the latest information on cryoEM
About the Author
Tony Crowther is an emeritus scientist at the MRC Laboratory of Molecular Biology in Cambridge, where he was joint head of the Structural Studies Division from 1994 to 2005. He has been involved in electron microscopy and image processing of biological structures for many years. His particular biological interests have been in viruses such as hepatitis B and in the abnormal filaments that form in neurodegenerative diseases. He is a Fellow of the Royal Society of London, a Fellow of the Academy of Medical Sciences and a member of the European Molecular Biology Organization.
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