Wow! eBook
Protein Quality Control in Neurodegenerative Diseases: 0 2013th Edition
Author(s): Richard I. Morimoto (Editor), Yves Christen
- Publisher: Springer
- Publication Date: 12 Dec. 2012
- Edition: 2013th
- Language: English
- Print length: 148 pages
- ISBN-10: 3642279279
- ISBN-13: 9783642279270
Book Description
The health of the proteome depends upon protein quality control to regulate the proper synthesis, folding, translocation, and clearance of proteins. The cell is challenged constantly by environmental and physiological stress, aging, and the chronic expressions of disease associated misfolded proteins. Substantial evidence supports the hypothesis that the expression of damaged proteins initiates a cascade of molecular events that leads to Alzheimer’s disease, Parkinson’s disease, amyotrophic lateral sclerosis, Huntington’s disease, and other diseases of protein conformation.
Editorial Reviews
Review
From the reviews:
“This is a very good cutting edge book of scholarly import on the functioning of molecules and signal transduction in both neurodegeneration and neuroprotection. … I recommend this book highly to scientists in disease pathophysiology work.” (Joseph J. Grenier, Amazon.com, June, 2014)
From the Back Cover
The health of the proteome depends upon protein quality control to regulate the proper synthesis, folding., translocation, and clearance of proteins. The cell is challenged constantyl by environmental and physiological stress, aging, and the chronic expressions of disease associated misfolded proteins. Substantial evidence supports the hypothesis that the expression of damaged proteins initiates a cascade of molecular events that leads to Alzheimer’s disease, Parkinson’s disease, amyotrophic lateral sclerosis, Huntington’s disease, and other diseases of protein conformation.
