Name: Probes and Tags to Study Biomolecular Function: for Proteins, RNA, and Membranes
Author: Lawrence W. Miller
ISBN: 9783527315666

Probes and Tags to Study Biomolecular Function: for Proteins, RNA, and Membranes book cover

Probes and Tags to Study Biomolecular Function: for Proteins, RNA, and Membranes

Author(s): Lawrence W. Miller

Publisher: Wiley-VCH
Publication Date: 23 July 2008
Edition: 1st
Language: English
Print length: 193 pages
ISBN-10: 3527315667
ISBN-13: 9783527315666

Book Description

The only resource to systematically review current experimental methods, this handy reference enables researchers to select the best solution for their experimental problems. For each method covered, the book provides step-by-step protocols, illustrated by typical research applications. After an initial section on probing the lipid bilayer, the text moves on to discuss probing proteins -- including membrane proteins -- and nucleic acids. The first single publication to incorporate chemical markers, fluorescent probes and genetic tags allows a well-informed comparison of different solutions for the same problem in molecular analytics.

Editorial Reviews

Review

"The book is a welcome addition to the literature that will be valued by a broad range of researchers in cell biology and biochemistry." (Doody's, May 2009)

"The quality of the book is good and its importance to the chemical community is high. I congratulate the editor on his first book. I am sure I will return to this book many times in the future." (Journal of the American Chemical Society, February 4, 2009)

From the Inside Flap

In order to study living cells and their component molecules, two basic strategies have emerged in recent years. The first is to apply a soluble marker molecule, a 'probe', that partitions to a particular cellular domain, and which can subsequently be measured. The second is to chemically or genetically modify a molecule of interest with a built-in probe, which is then called a 'tag'.
This handy reference systematically reviews current experimental methods and enables researchers to select the best solution for their experimental problems. For each method covered, the book provides step-by-step protocols, illustrated by typical research applications. Commencing with probing the lipid bilayer, the text then moves on to discuss probing proteins -- including membrane proteins -- and nucleic acids. This is the first single publication to incorporate chemical markers, fluorescent probes and genetic tags to allow a well-informed comparison of different solutions for similar problems in molecular analytics.

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Probes and Tags to Study Biomolecular Function: for Proteins, RNA, and Membranes

Probes and Tags to Study Biomolecular Function: for Proteins, RNA, and Membranes

Book Description

Editorial Reviews

Review

From the Inside Flap

From the Back Cover

About the Author

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