Wow! eBook
Primary Aldosteronism: Molecular Genetics, Endocrinology, and Translational Medicine Softcover reprint of the original 1st ed. 2014 Edition
Author(s): Per Hellman
- Publisher: Springer
- Publication Date: 23 Aug. 2016
- Edition: Softcover reprint of the original 1st ed. 2014
- Language: English
- Print length: 244 pages
- ISBN-10: 1493946226
- ISBN-13: 9781493946228
Book Description
Primary Aldosteronism (PA) is a disease caused by the overproduction of aldosterone hormone from the adrenal glands. PA causes hypertension and the majority with this disease are undiagnosed for PA. There are new insights into this matter by using biochemistry as well as advanced radiology. In 2011, a breakthrough in the genetic derangements came, identifying a mutated potassium channel gene – KCNJ5 – in about 40% of PA with adenoma. Chapters in this book include a history of the disorder, epidemiology, genetics derangements, the KCNJ5 mutations and phenotype and more.
