Practical Synthetic Organic Chemistry: Reactions, Principles, and Techniques

“The last sentence by editor Caron is an appropriate conclusion: “Building each chapter … served as an excellent chemistry refresher course for the authors, and we learned a lot of new chemistry in the process.” Chemists everywhere will applaud their efforts and.”  (Angewandte Chemie, 2012)

“The book is extremely good value, partly because it is not available in hardback and whilst this may please budget-holders initially, it also is another good reason for looking forward to a second edition. . . Overall, apart from one or two very minor complaints, this book is highly recommended, in fact it should be a must for all practising synthetic organic chemists.” (Organic Process Research & Development Journal, 2011)

“…an emphasis on practicality, scalability and efficiency… I would imagine this will be a popular teaching text in universities but it should also be read by process chemists for an insight into good synthetic organic chemistry and route design. It looks excellent value for money.” (Scientific Update, 2011)

A hands-on guide to assist in the planning and execution of synthetic reactions in the laboratory

Despite the maturity of organic chemistry, it can still be very challenging to identify optimal methods for synthetic transformations that perform as well in real-world manufacturing processes as they do in the laboratory. This detailed and accessible guide attempts to address this vexing issue and deliver proven methodologies practicing synthetic chemists will find valuable for identifying reaction conditions that work reliably over the broadest possible range of substrates.

Practical Synthetic Organic Chemistry:

• Provides a practical guide to strategically planning and executing chemical syntheses for the bench chemist in industry

• Discusses information that is not common knowledge beyond the boundaries of process chemistry groups, such as the synthetic routes of selected contemporary pharmaceutical drugs and practical solvents, as well as green chemistry concepts

• Highlights key reactions, including substitutions, additions, eliminations, rearrangements, oxidations, and reductions

• Addresses basic principles, mechanisms, advantages and disadvantages of the methodology, and techniques for achieving laboratory success

Incorporating such an extraordinary wealth of information on organic chemistry and its related fields into one complete volume distinguishes Practical Synthetic Organic Chemistry as an incomparable desktop reference for professionals—and an invaluable study aid for students.