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Photodynamic Inactivation of Microbial Pathogens: Medical and Environmental Applications: Volume 11
Author(s): Michael R Hamblin
- Publisher: Royal Society of Chemistry
- Publication Date: 13 Jun. 2011
- Language: English
- Print length: 434 pages
- ISBN-10: 1849731446
- ISBN-13: 9781849731447
Book Description
The first book to comprehensively cover the use of light and photosensitising agents for controlling the population of microbial pathogens.
Editorial Reviews
From the Back Cover
About the Author
Dr Michael R. Hamblin is a Principal Investigator at the Wellman Center for Photomedicine at Massachusetts General Hospital and an Associate Professor of Dermatology at Harvard Medical School. He received his PhD in synthetic organic chemistry from Trent University in England. His interests lie in photodynamic therapy for infections, cancer, and heart disease and also in low-level light therapy for wound healing, arthritis, traumatic brain injury and hair regrowth. His research program is supported by NIH, CDMRP and CIMIT among others. He has published over 125 peer-reviewed articles, over 120 conference proceedings, book chapters and international abstracts, and holds 8 patents.
Excerpt. © Reprinted by permission. All rights reserved.
Photodynamic Inactivation of Microbial Pathogens: Medical and Environmental Applications
By Michael R. Hamblin, Giulio Jori
The Royal Society of Chemistry
Copyright © 2011 European Society for Photobiology
All rights reserved.
ISBN: 978-1-84973-144-7
Contents
Chapter 1 Antimicrobial Photodynamic Therapy: Basic Principles Giulio Jori, Monica Camerin, Marina Soncin, Laura Guidolin and Olimpia Coppellotti,
Chapter 2 Phenothiazinium Salts as Antimicrobial Photosensitizing Agents Mark Wainwright,
Chapter 3 Approaches to Kill Gram-negative Bacteria by Photosensitized Processes Yeshayahu Nitzan and Izabella Pechatnikov,
Chapter 4 Innovative Design of Antimicrobial Photosensitizers Michael R. Hamblin, Sulbha K. Sharma and Gitika B. Kharkwal,
Chapter 5 Porphyrins as Antimicrobial Photosensitizing Agents A. Almeida, A. Cunha, M. A. F. Faustino, A. C. Tomé and M. G. P. M. S. Neves,
Chapter 6 Fullerene Derivatives as Antimicrobial Photosensitizing Agents M. Elisa Milanesio and Edgardo N. Durantini,
Chapter 7 Photosensitizer Delivery for Photodynamic Antimicrobial Chemotherapy Ryan F. Donnelly, Corona M. Cassidy and Michael M. Tunney,
Chapter 8 Photodynamic Therapy of Localized Infections in Animal Models Tianhong Dai and Michael R. Hamblin,
Chapter 9 Pathogen Reduction in Blood for Transfusion Using Photodynamic Treatments Ehud Ben-Hur and Raymond P. Goodrich,
Chapter 10 PDT for Acne Michael H. Gold,
Chapter 11 PDT for Viral Lesions Michael H. Gold,
Chapter 12 PDT For Cutaneous Leishmaniasis Oleg E. Akilov, Ulysses W. Sallum and Tayyaba Hasan,
Chapter 13 Antimicrobial Photodynamic Therapy (aPDT) for Oral Infections Jonathan Pratten, Veronique Benhamou and Cale Street,
Chapter 14 Photodynamic Antifungal Chemotherapy P. G. Calzavara-Pinton, M. T. Rossi and B. Ortel,
Chapter 15 Photodynamic Therapy for Wound Infections Stanley B. Brown and Clare L. Conway,
Chapter 16 Photodynamic Therapy for Helicobacter pylori Infections Javad T. Hashmi and Michael R. Hamblin,
Chapter 17 Inactivation of Microbial Pathogens by Photosensitized Processes: Environmental Applications Michela Magaraggia, Olimpia Coppellotti, Clara Fabris, Laura Guidolin and Giulio Jori,
Subject Index,
CHAPTER 1
Antimicrobial Photodynamic Therapy: Basic Principles
Giulio Jori, Monica Camerin, Marina Soncin, Laura Guidolin and Olimpia Coppellotti
Department of Biology, University of Padova, Via Ugo Bassi 58B, 35131 Padova, Italy
Table of Contents
1.1. Introduction
1.2. Photosensitized Inactivation of Microbial Cells: General Aspects
1.2.1. The Target
1.2.2. Photobiological Processes in the Photosensitized Inactivation of Microbial Cells
1.2.3. The Photosensitizer
1.3. Kinetics and Mechanism of the Photosensitized Inactivation of Microbial Cells
1.4. Conclusions
References
1.1. Introduction
Photodynamic therapy (PDT) represents a well-established modality for the treatment of a variety of malignant tumours; on the other hand, this technique is presently being extended to several non-cancerous conditions, especially those which are characterized by overgrowth of unwanted or abnormal cells, such as inter alia several dermatological diseases, benign prostatic hyperplasia and age-related macular degeneration. An increasing amount of attention is also being focused on the application of PDT for the treatment of infectious diseases. In actual fact, the possibility to kill microorganisms by the combined action of visible light and a photosensitizing dye wa
