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Next Generation Sequencing in Cancer Research: Volume 1: Decoding the Cancer Genome Softcover reprint of the original 1st ed. 2013 Edition
Author(s): Wei Wu (Editor), Hani Choudhry
Publisher: Springer
Publication Date: August 25, 2015
Edition: Softcover reprint of the original 1st ed. 2013
Language: English
Print length: 395 pages
ISBN-10: 1489988084
ISBN-13: 9781489988089
Book Description
This volume provides an interdisciplinary perspective of applying Next Generation Sequencing (NGS) technology to cancer research. It aims to systematically introduce the concept of NGS, a variety of NGS platforms and their practical implications in cancer biology.This unique and comprehensive text will integrate the unprecedented NGS technology into various cancer research projects as opposed to most books which offer a detailed description of the technology. This volume will present true experimental results with concrete data processing pipelines, discuss the bottleneck of each platform for real project in cancer research. In additional, single cancer cell sequencing as the proof of concept will be introduced in this book, along with cutting-edge information provided will help the intended audience to develop a comprehensive understanding of the NGS technology and practical whole genome sequencing data analysis and rapidly translate into their own research, specifically in the field of cancer biology.
Editorial Reviews
From the Back Cover
Next Generation Sequencing (NGS) technology has placed important milestones in the life science and changed the direction in biomedical science inclucing cancer. Scientists around the world are attempting to find the root cause of cancer and they are looking for more direct and effective means to cure cancer. This journey to conquer cancer is more optimistic now with the unfolding of the cancer genome. This book focuses on the application of various NGS in the frontier cancer genome research. The 18 chapters in this volume have been written by scientists with many outstanding contributions in their area and the join effort has created comprehensive insightful view on (1) Overview of next generation sequencing technology in cancer genome research (2) Genome regulation and targeted sequencing in cancer (3) RNA transcriptome (coding and non-coding) in cancer genome (4)The challenges of computational biology for cancer genome study.
This book is a state-of-the-art reference to all scientific researchers and onologists who are interested in the understanding of the cancer initiatome at whole genome scale and to those are keen to translate the ‘base pairs to bedside’ for better management of cancer patients in the era of personalized medicine.
About the Author
Wei Wu, M.D., Ph.D. is a Research Associate for the Department of Bio Science at the University of Calgary, specializing in the cancer genome and systems biology. He has edited two volumes with Springer. In addition, he’s a member of various editorial board for journals including the International Journal of Biomedical Sciences, International Journal of Molecular Medicine and Advances in Sciences and the Research Journal of Biological Sciences. Hani Choudhry, D.Phil is a member of the Genomics Research Group at the Wellcome Trust Centre for Human Genetics at Oxford University. His expertise is in high throughput next generation sequencing.