Multidimensional Liquid Chromatography: Theory and Applications in Industrial Chemistry and the Life Sciences

MDLC: A Real-Life, Real-Lab Resource

Multidimensional Liquid Chromatography (MDLC) is a very powerfulseparation technique for analyzing exceptionally complex samples in onestep. This authoritative reference presents a number of recent contributions that help define the current art and science of MDLC. Topics covered include instrumentation, theory, methods development, and applications of MDLC in the life sciences and in industrial chemistry. With the information to help readers perform very difficult separations of complex samples, this reference:

• Includes introductory chapters on theory and instrumentation

• Focuses on techniques that incorporate separations carried out in the liquid phase and by columns, and on those in which the use of the comprehensive mode prevails but is not exclusive

• Covers applications to research in polymer and industrial analysis, pharmaceuticals, and proteomics and other life sciences

• Features chapters contributed by leading experts or teams of experts

With a practical combination of theory and applications, Multidimensional Liquid Chromatography: Theory and Applications in Industrial Chemistry and the Life Sciences shows readers how to use MDLC to solve real-life,real-lab problems. A core reference for pharmaceutical and life scienceresearchers and for analytical chemists in various industries, it also providesan overview for practitioners who are new in their fields. In addition, it is an excellent resource for graduate students and postdoctoral fellows in academic laboratories.

Steven A. Cohen, PhD, is Life Sciences Director, RDE of the Proteomics Technology Group at the Waters Corporation in Milford, Massachusetts.

MARK R. SCHURE, PhD, is Technical Director of the Computational Chemistry Group and Technical Director of the Theoretical Separation Science Laboratory at the Rohm and Haas Company in Springhouse, Pennsylvania.