Mouse Genetics and Transgenics: A Practical Approach
Author(s): Ian J. Jackson (Editor), Catherine M. Abbott
- Publisher: Oxford University Press
- Publication Date: 9 Mar. 2000
- Edition: Illustrated
- Language: English
- Print length: 324 pages
- ISBN-10: 0199637083
- ISBN-13: 9780199637089
Book Description
A unique book that integrates knowledge from a wide range of expertise, specifically applied to the mouse, and addressed at a wide audience from those new to the field to experts who want an update on the state of the art. Mouse Genetics and Transgenics: APA covers all aspects of using the mouse as a genetic model organism: care & husbandry; archiving stocks as frozen embryos or sperm; making new mutations by chemical mutagenesis; transgenesis; and gene targetting; mapping mutations and polygenic traits by cytogenetic, genetic, and physical means; and disseminating and researching information via the Internet.
Editorial Reviews
Review
... provides a major source of information on the mouse as an experimental model, and can be used as a detailed manual for researchers ... offers tried-and-tested protocols, with handy trouble-shooting tips and other supporting advice. It is aimed for both scientists new to the field and those who want an overview of the latest techniques. Index at the end of the book facilitates quick orientation and selective reading. Croatian Medical Journal (CMJ)
Review
Covers all aspects of using the mouse as genetic model organism.
Review
"An authoritative manual covering all aspects of the production and analysis of mouse mutants and transgenic mice. Initial chapters discuss animal husbandry and cryopreservation methods. This is followed by discussions of various genetic and physical mapping techniques, as well as applications of fluorescence in situ hybridisation (FISH). The final part details the production of transgenic animals from plasmids, BACS and YACS as well as methods of making new mutants by chemical mutagenesis or by targeting ES cells. An excellent resource describing the many databases accessible via the Internet."--Aslib Book Guide
View on Amazon
Wow! eBook
