
Mismatch: The Lifestyle Diseases Timebomb
Author(s): Peter Gluckman (Author)
- Publisher: Oxford University Press, USA
- Publication Date: 7 April 2008
- Language: English
- Print length: 304 pages
- ISBN-10: 0199228388
- ISBN-13: 9780199228386
Book Description
Our bodies evolved to allow our ancestors the best chance of survival as hunter-gatherers in the Savannah. Our brains, on the other hand, have allowed us to develop complex societies, cultures, and lifestyles, far removed from those of our ancestors. As a result, write Peter Gluckman and Mark Hanson in Mismatch, we have created a modern, artificial world that is painfully out of tune with our evolved bodies. In a compelling narrative that begins with the Sherpa in Nepal, Gluckman and Hanson, both leading medical scientists, draw on the latest research, bringing together concepts from evolutionary biology, developmental science, medicine, anthropology and ecology to describe the nature of this mismatch, its consequences, and how we may counter it. The authors reveal that this mismatch has led to the current deadly explosion in “lifestyle” diseases such as diabetes and obesity, and it may well lead to increasingly frequent epidemics. There are broader consequences too for societies, such as the falling age of puberty, with its attendant mismatch with psychological maturity, and at the other end of life, the implications of increasing longevity. Is there any way out? Yes, say the authors. They propose that intervention in early human development, alongside a better focus on the health of potential mothers, can make future generations better suited to the modern world. In this remarkable and lucidly written book, Gluckman and Hanson identify a profound and growing problem that we ignore at our peril.
Editorial Reviews
Review
Review from previous edition Thought-provoking…this book conveys admirably, for a non-specialist reader, the implications of an important idea. (Michael Sargent, Nature)
Compelling book (
Laura Howes, Chemistry World)Essential reading for anybody interested in the fascinating complexities of human biology…A most timely and innovative contribution to the popular debate about genes and the environment. (
Robert Winston, from the Foreword)A fascinating and important journey through the development and evolution of human health. (
Lewis Wolpert)…possible solutions are suggested here, but for the most part Hanson and Gluckman just lay the cards out on the table for you to contemplate, which is refreshing. They offer a very humane insight that can help us all make sense of the modern world and our place in it. (
Margaret Bartlett, Health and Fitness)About the Author
Peter Gluckman is University Distinguished Professor, Professor of Pediatrics and Perinatal Biology, and Director of the Liggins Institute for Medical Research and the National Center for Growth and Development, at the University of Auckland. Mark Hanson directs the Centre for Developmental Origins of Health and Disease at the University of Southampton, and is an Honorary Fellow of the Royal College of Obstetricians and Gynecologists, and Honorary Professor at the University of Auckland.
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