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Mechanisms and Models in Rheumatoid Arthritis
Author(s): E. R. Pettipher (Editor), B. Henderson (Author), J. C. W. Edwards (Author)
- Publisher: Academic Press Inc
- Publication Date: 1 Feb. 1995
- Language: English
- Print length: 440 pages
- ISBN-10: 0123404401
- ISBN-13: 9780123404404
Book Description
Mechanisms and Models in Rheumatoid Arthritis brings together a group of eminent researchers from the fields of clinical rheumatology, pathology, experimental pathology, immunology, connective tissue biochemistry, microbiology, pharmacology and developmental biology to describe the current views of the cellular and humoral mechanisms that drive the pathology of rheumatoid arthritis and experimental models of rheumatoid arthritis.
Key Features:
* The book is divided into five sections:
* The clinical spectrum, aetiopathogenesis, the role of microbial superantigens in pathology and the present and future therapies for rheumatoid arthritis
* The pathology of rheumatoid arthritis, the development and role of synovial pannus and the use of immunohistochemistry in defining synovial pathology
* Cell populations involved in synovitis with chapters on synovial cells, chondrocytes, bone cells, leukocytes and leukocyte trafficking
* Mediators, with coverage of: cytokines and cytokine inhibitors, growth factors, free radicals and inflammatory lipid mediators, neuropeptides and proteases
* Current studies on experimental models of rheumatoid arthritis
