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Ligand Efficiency Indices for Drug Discovery: Towards an Atlas-Guided Paradigm
Author(s): Celerino Abad-Zapatero (Author)
- Publisher: Academic Press
- Publication Date: 5 Feb. 2013
- Edition: Illustrated
- Language: English
- Print length: 178 pages
- ISBN-10: 0124046355
- ISBN-13: 9780124046351
Book Description
Editorial Reviews
Review
“For those interested in a fresh interpretation of the utility of ligand efficiency indexes for drug discovery, this book serves as a nice introduction to a more modern, graphical approach to drug lead identification.” —Doody.com, August 16, 2013
“Abad-Zapatero presents a novel approach to drug discovery that is based on the notion that a change of variables is necessary. The algebraic framework he proposes combines the affinity between ligands and targets with the physico-chemical properties of the ligands to construct a set of novel variables that can map chemico-biological space (CBS) and optimize the drug-discovery process.” —Reference and Research Book News, August 2013
Review
A guided ‘mini-atlas’ of the content of Chemico-Biological Space with snapshots, postcards and views of the chemistry and biology related to pharmacology, medicine and drug-discovery
