Inflammasome Biology: Fundamentals, Role in Disease States, and Therapeutic Opportunities
Author(s): Pelegrin
Publisher: Academic Press
Publication Date: 5 Dec. 2022
Edition: 1st
Language: English
Print length: 672 pages
ISBN-10: 0323918026
ISBN-13: 9780323918022
Book Description
Inflammasome Biology: Fundamentals, Role in Disease States, and Therapeutic Opportunities is a complete reference on the role of inflammasomes in health and disease. Sections cover the different types of inflammasomes, including cellular signaling, structural and evolutive aspects, overview the role of inflammasomes in key diseases, microbial infections and human body systems conditions, cover the interplay between Inflammasomes and cell death processes, and discuss current therapeutic opportunities driven by inflammasome research, including targeting, blocking and inhibiting the development of inflammasomes through both synthetic and natural compounds.
This book is the perfect reference for cell biologists, immunologists and research clinicians to understand the foundations of inflammasomes and explore the therapeutic opportunities they present. Pharma researchers may also find this reference invaluable in devising new approaches to developing anti-inflammatory drugs.
Provides comprehensive coverage of the subject of inflammasome biology
Authored by leading experts worldwide
Provides biological insights that have both health implications and therapeutic potential
Editorial Reviews
Review
The most complete reference on Inflammasomes for biomedical scientists
From the Back Cover
Inflammasome Biology is a complete reference on the role of inflammasomes in health and disease. The Editor worked with the most productive researchers worldwide in inflammasomesto organize consistent coverage of the subject, from basic biology to therapeutic potential. Divided in four main sections, the book covers the different types of inflammasomes in part I, including cellular signaling, structural and evolutive aspects. Part II offers extensive overviews of the role of inflammasomes in key diseases, microbial infections, and human body systems conditions. Part III is dedicated to the interplay between Inflammasomes and cell death processes. The final part covers the current therapeutic opportunities driven by inflammasome research, including targeting, blocking, and inhibiting the development of inflammasomes through both synthetic and natural compounds. Inflammasome Biology is the perfect reference for cell biologists, immunologists, and research clinicians to understand the foundations of inflammasomes and explore the therapeutic opportunities they present. Pharma researchers may also find this reference invaluable in devising new approaches to developing anti-inflammatory drugs.
About the Author
Dr. Pablo Pelegrin is the principal investigator of the molecular inflammation research group at the Murcia BioHealth Research Institute-Hospital “Virgen de la Arrixaca in, Murcia, Spain. He has postdoctoral degrees from both the University of Manchester (UK), and from the University of Sheffield (UK). His PhD in developmental immunology was obtained with the University of Murcia. He is an honorary lecturer at the University of Manchester, and Editor of the Inflammasome Journal, published by De Gruyter Open. Dr. Pelegrin has researched the Inflammasome for the past 15 years and is one of the most prolific researchers in this multidisciplinary research area.
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