Hydrophilic Interaction Liquid Chromatography (HILIC) and Advanced Applications

Hydrophilic Interaction Liquid Chromatography (HILIC) and Advanced Applications book cover

Hydrophilic Interaction Liquid Chromatography (HILIC) and Advanced Applications

Author(s): Perry G. Wang (Editor), Weixuan He

  • Publisher: Routledge
  • Publication Date: 22 May 2017
  • Edition: 1st
  • Language: English
  • Print length: 616 pages
  • ISBN-10: 1138113395
  • ISBN-13: 9781138113398

Book Description

This is the first book that comprehensively and systematically describes the new technology of hydrophilic interaction liquid chromatography (HILIC). Hydrophilic interaction chromatography is a separation technique suitable for polar and hydrophilic compounds and orthogonal to reversed phase liquid chromatography. From small organic molecules to proteins, the text explores the many applications of HILIC in the analytical field. Winner of the President's Award for Excellence, the author explains how HILIC can significantly improve analytical throughput by shortening sample preparation procedure, which is one of the bottlenecks for drug discovery and development in the pharmaceutical industry.

Editorial Reviews

Review

"[This book] contains a collection of case studies of practical importance, illustrating the development, optimization, and validation of HILIC methods for particular separation problems. Most chapters are clearly written, with emphasis on the experimental detail, and contain very useful up-to-date references. Researchers in analytical and bioanalytical chemistry may find this reference book useful."
―P. Jandera,
Anal Bioanal Chem (2012) 404:11–12

From the Back Cover

This is the first book that comprehensively and systematically describes the new technology of hydrophilic interaction liquid chromatography (HILIC). Hydrophilic interaction chromatography is a separation technique suitable for polar and hydrophilic compounds and orthogonal to reversed phase liquid chromatography. From small organic molecules to proteins, the text explores the many applications of HILIC in the analytical field. Winner of the President's Award for Excellence, the author explains how HILIC can significantly improve analytical throughput by shortening sample preparation procedure, which is one of the bottlenecks for drug discovery and development in the pharmaceutical industry.

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