Hydrophilic Interaction Liquid Chromatography (HILIC) and Advanced Applications
Author(s): Perry G. Wang (Editor), Weixuan He
Publisher: Routledge
Publication Date: 22 May 2017
Edition: 1st
Language: English
Print length: 616 pages
ISBN-10: 1138113395
ISBN-13: 9781138113398
Book Description
This is the first book that comprehensively and systematically describes the new technology of hydrophilic interaction liquid chromatography (HILIC). Hydrophilic interaction chromatography is a separation technique suitable for polar and hydrophilic compounds and orthogonal to reversed phase liquid chromatography. From small organic molecules to proteins, the text explores the many applications of HILIC in the analytical field. Winner of the President's Award for Excellence, the author explains how HILIC can significantly improve analytical throughput by shortening sample preparation procedure, which is one of the bottlenecks for drug discovery and development in the pharmaceutical industry.
Editorial Reviews
Review
"[This book] contains a collection of case studies of practical importance, illustrating the development, optimization, and validation of HILIC methods for particular separation problems. Most chapters are clearly written, with emphasis on the experimental detail, and contain very useful up-to-date references. Researchers in analytical and bioanalytical chemistry may find this reference book useful." ―P. Jandera, Anal Bioanal Chem (2012) 404:11–12
From the Back Cover
This is the first book that comprehensively and systematically describes the new technology of hydrophilic interaction liquid chromatography (HILIC). Hydrophilic interaction chromatography is a separation technique suitable for polar and hydrophilic compounds and orthogonal to reversed phase liquid chromatography. From small organic molecules to proteins, the text explores the many applications of HILIC in the analytical field. Winner of the President's Award for Excellence, the author explains how HILIC can significantly improve analytical throughput by shortening sample preparation procedure, which is one of the bottlenecks for drug discovery and development in the pharmaceutical industry.
About the Author
Perry G. Wang is currently Principal Scientist at Teleflex Medical in Wyomissing, Pennsylvania.