The Genetics and Development of Scoliosis Second Edition 2018 Edition
Author(s): Kenro Kusumi (Editor), Sally L. Dunwoodie
Publisher: Springer
Publication Date: 15 Jan. 2019
Edition: Second Edition 2018
Language: English
Print length: 211 pages
ISBN-10: 3030079449
ISBN-13: 9783030079444
Book Description
Our understanding of the genetic and developmental mechanisms underlying scoliosis is rapidly evolving, this timely second edition of The Genetics and Development of Scoliosis Second Edition 2018 Edition is to provide researchers, clinicians, and students with the most current views in this field.
This volume brings together leaders in understanding congenital and idiopathic scoliosis to present the current state of research, and to compare the genetic etiology of these conditions, in order to identify potential shared developmental mechanisms. This book will summarize the recent advances in studies of spinal development and how disruptions during embryogenesis in embryonic segmentation can lead to congenital vertebral defects. In addition, recent reports of genetic loci predisposing patients to develop juvenile and adolescent idiopathic scoliosis will be presented, and key clinical features are reviewed. Finally, there will be discussion of how genetic heterogeneity and gene-environment interactions may contribute to congenital scoliosis and isolated vertebral malformations.
Editorial Reviews
Review
“The book is aimed at researchers, clinicians, and students involved in the treatment of patients with idiopathic and congenital scoliosis. Orthopedic surgeons, rehabilitation specialists, clinical geneticists, and primary care providers in particular may find information about abnormal spinal curvatures of interest. … Not many books are exclusively dedicated to specific genetic disorders such as this one. … This is a well-done review that will be a useful consultation resource for clinicians.” (Luis F Escobar, Doody’s Book Reviews, January 31, 2020)
From the Back Cover
Our understanding of the genetic and developmental mechanisms underlying scoliosis is rapidly evolving, this timely second edition of The Genetics and Development of Scoliosis Second Edition 2018 Edition is to provide researchers, clinicians, and students with the most current views in this field.
This volume brings together leaders in understanding congenital and idiopathic scoliosis to present the current state of research, and to compare the genetic etiology of these conditions, in order to identify potential shared developmental mechanisms. This book will summarize the recent advances in studies of spinal development and how disruptions during embryogenesis in embryonic segmentation can lead to congenital vertebral defects. In addition, recent reports of genetic loci predisposing patients to develop juvenile and adolescent idiopathic scoliosis will be presented, and key clinical features are reviewed. Finally, there will be discussion of how genetic heterogeneity and gene-environment interactions may contribute to congenital scoliosis and isolated vertebral malformations.
About the Author
Kenro Kusumi, Ph.D., is a Professor in the School of Life Sciences at Arizona State University.Dr. Kusumi’s current research focuses on genomic analysis of spinal development and regeneration, and their applications to developing novel therapies for scoliosis and other spinal disorders.
Sally L. Dunwoodie, Ph.D., is a Professor at the University of New South Wales and Laboratory Head in the Developmental Biology and Stem Cell Division at the Victor Chang Cardiac Research Institute in Sydney. Dr. Dunwoodie’s research focuses on identifying genetic and environmental factors that disrupt embryogenesis and cause birth defects.
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