Wow! eBook
Gene Therapy 2010th Edition
Author(s): Mauro Giacca (Author)
- Publisher: Springer
- Publication Date: December 13, 2014
- Edition: 2010th
- Language: English
- Print length: 324 pages
- ISBN-10: 8847055555
- ISBN-13: 9788847055551
Book Description
I entered the gene therapy field in the mid-1990s, being fascinated by the immense potential of genes as drugs for the treatment of human disease. Since then, I have experienced the ups and downs of this discipline, and tried to contribute with my work and that of my laboratory to the development of innovative approaches to the treatment of cardiovascular disorders. During these years, I have had several opp- tunities to speak on gene therapy at lectures and academic lessons, and have often noticed that the field is very attractive to scientists of all disciplines. However, as yet no comprehensive book on the subject has been published. Indeed, most books in the field are either a collection of gene transfer laboratory protocols or deal with the subject in a rather superficial manner. Hence the idea to write a gene therapy textbook that is broad and comprehensive, but at the same time provides sufficient molecular and clinical detail to be of interest to students, professors, and specialists in the various disciplines that contribute to gene therapy. I have tried to keep the language plain and, whenever possible, non-technical. Since the book is intended to be a textbook in the field of gene therapy in both the basic science and clinical areas, whenever technical descriptions are required, they are provided.
Editorial Reviews
From the Back Cover
This book presents to the reader a comprehensive and detailed, yet easily accessible, description of the whole field of gene therapy. It covers topics ranging from vector development to the results of the most recent clinical trials. It includes descriptions of lentiviral and AAV vector development, of therapeutic gene selection (including siRNAs, shRNAs, and microRNAs), and of the most recent clinical applications of gene therapy for diseases of the eye, the cardiovascular system, and the central nervous system. Of note, the book only considers conditions for which transfer of genetic material has already progressed to clinical applications or is close to doing so. The language is plain and, whenever possible, non-technical. Since the book is intended to be a textbook in the field of gene therapy in both the basic science and clinical fields, whenever technical descriptions are required these are provided. Readers will include graduate students in the life sciences area in their final years of study, PhD students, and medical doctors specializing in different fields of internal and specialist medicine, in addition to research scientists working in various areas of current biomedical research.
About the Author
Mauro Giacca, MD, PhD, is the Director of the Italian Component of the International Centre for Genetic Engineering and Biotechnology (ICGEB), an international research organisation based in Trieste, Italy, and full professor of molecular biology at the Faculty of Medicine of the University of Trieste. Over the last 20 years, he has participated in the front line in the development of the gene therapy field. He is internationally recognized as an expert in AAV vector biology and in the application of AAV vectors for the gene therapy of cardiovascular disorders.
