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Gene Genealogies, Variation And Evolution: A Primer in Coalescent Theory
Author(s): Jotun Hein (Author)
- Publisher: Oxford University Press, U.S.A.
- Publication Date: 17 Feb. 2005
- Edition: Illustrated
- Language: English
- Print length: 292 pages
- ISBN-10: 0198529961
- ISBN-13: 9780198529965
Book Description
Coalescent theory tells us what gene genealogies are expected to look like if populations have different demographic histories – i.e, population size, structure, etc. The aim of this book is to provide an accessible introduction to Coalescent Theory with a view towards data analysis. Coalescent Theory has in the last two decades moved from being an obscure technique that appealed to mathematical population geneticists to a central tool in data analysis of D.N.A. sequences. The completion of the sequencing of the human genome and accompanying determination of S.N.Ps and haplotypes will increase its importance even further. This textbook, rich in examples and illustrations, is suitable for a graduate course in statistics, population-, molecular-, and medical genetics.
Editorial Reviews
Review
an excellent and timely book that should appeal to a variety of people in genetics and applied mathematics. ― Professor Montgomery Slatkin (Berkeley)
the authors are outstanding experts in the field, and the book is topical and timely. ―
Professor David Balding (Imperial College)Hein, Schierup and Wiuf have written the first general book on the coalescent. It is an engaging combination of clear mathematical derivation and real data examples. ―
Professor Joe Felsenstein (University of Washington)Book Description
The aim of this book is provide an accessible introduction to Coalescent Theory with a view towards data analysis.
