Emerging Concepts of Tumor Exosome-Mediated Cell-Cell Communication
Editorial Reviews
From the Back Cover
Tumor exsome-mediated cell-cell communication has grown increasingly important in cancer research. Recent findings on vesicle-based information transfer by exosomes have changed our view of the tumor microenvironment. Currently, exosomes represent the main extracellular processes implicated in the regulation of multiple physiological processes. Importantly, in cancer, exosomes contribute to the formation of the tumor microenvironment, promoting invasion, angiogenesis, immune regulation and metastasis. Therefore, exosomes could be considered one of the major forces acting locally or systemically to promote the continuous crosstalk between the tumor and its microenvironment, influencing the behavior of different cell types such as stromal, endothelial and bone marrow-derived cells. Given the ability of exosomes to export unneeded endogenous molecules from cells, these structures hold great potential as anticancer therapeutic agents. This volume gives a comprehensive review on current research in this area and also discuss future prospects as prognostic markers for cancer.
Book Description
Hardcover: 227 pages
Publisher: Springer; 2013 edition (September 6, 2012)
Language: English
ISBN-10: 1461436966
ISBN-13: 9781461436966
Huang-Ge Zhang(Editor)
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