Disorders of Hemoglobin: Genetics, Pathophysiology, and Clinical Management
Author(s): Martin H. Steinberg (Editor), Bernard G. Forget (Editor), Douglas R. Higgs (Editor), Ronald L. Nagel (Editor), H. Franklin Bunn (Foreword)
Publisher: Cambridge University Press
Publication Date: 18 Dec. 2000
Language: English
Print length: 1282 pages
ISBN-10: 0521632668
ISBN-13: 9780521632669
Book Description
The first comprehensive reference on the genetic and acquired disorders of hemoglobin in over a decade, Disorders of Hemoglobin stands out as the definitive work on the genetics, pathophysiology, and clinical management of this wide-range of disorders. Drs. Steinberg, Forget, Higgs, and Nagel have gathered the absolute world authorities on the science and clinical management of thalassemias, sickle cell disease, and other inherited and acquired hemoglobinopathies to create the authoritative textbook for researchers and clinicians alike. Divided into eight distinct sections, coverage spans the molecular and genetic basis of hemoglobinopathies and thalassemias, their epidemiology and genetic selection, and the diagnosis and special treatments of b and a thalassemias, sickle cell disease, Hb E, unstable hemoglobins, Hb M disorders, and acquired and secondary disorders of hemoglobin. Clinical features of all disorders are anchored to the scientific and pathophysiological events which precede them; providing clinicians with a clear scientific background of the disorders they treat and scientists with an essential link between their research and its clinical manifestation. Disorders of Hemoglobin is the only single-source reference of its kind for hematologists, internists, pediatricians, clinical investigators, and geneticists worldwide.
Editorial Reviews
Review
‘The first chapter sets the stage by providing a comprehensive historical perspective. The high quality of the book continues from there … this book will be invaluable to experts in the field and extremely useful to medical students and house officers who want a single resource in which to review the clinical aspects of hemoglobin disorders.’ New England Journal of Medicine
‘Disorders of Hemoglobin provides a comprehensive review of both the scientific and the clinical aspects of human erythropoiesis and its disorders. It offers a collection of well written chapters by leading international investigators, many of whom are able to refer to the contribution their own research work has made to the field … comprehensive, detailed and well written … a fine and accessible text that can be recommended for students, scientists and clinicians who seek detailed reviews of red-cell disorders and their clinical management.’ Journal of the Royal Society of Medicine
‘The fact that a book of this size and scope is devoted to a single protein is an indication of the wondrous complexity of biology and a harbinger of what still lies ahead … it is a superb exposition of current knowledge, and I am very happy to have a copy on my shelf.’ Oncology
Book Description
Disorders of Hemoglobin stands out as the definitive work on the genetics, pathophysiology, and clinical management of hemoglobinopathies and thalassemia.
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