Complete, up-to-date collection of available catalytic systems and processes
Reviewing the latest advances in copper-catalyzed reactions for the formation of carbon-heteroatom and carbon-carbon bonds, this book enables readers to understand what is currently known and possible in the field, as well as where additional research is still needed. The book's comprehensive coverage offers insights into the underlying mechanisms, preparation procedures, and state-of-the-science strategies for copper-catalyzed reactions. Moreover, readers will find a complete collection of available reactions, catalytic systems and processes, as well as current and pending patents.
Starting with the Ullmann and Goldberg cross-coupling reactions, Copper-Mediated Cross-Coupling Reactions describes core applications and key advances in the field. The first two sections are dedicated to the formation of C-heteroatom bonds and C-C bonds. The third section explores applications of copper-catalyzed cross-coupling reactions, including industrial uses, and the development of environmentally friendly reactions. Among the highlights of coverage, readers will discover:
- Advances that have revolutionized pharmaceutical, polymer, and materials synthesis
- Copper-mediated procedures that have been successfully employed to assemble complex targets
- Advantages and limitations of using different catalytic systems and cross-coupling partners
- Copper-catalyzed cross-coupling reactions in natural product/bioactive molecule synthesis
- New methods for conducting copper-mediated reactions with supported catalysts that enable recyclable and reusable systems
The book features contributions from an international team of experts and pioneers in the field. Chapters are based on a thorough review and analysis of the literature as well as the authors' firsthand experience.
By setting forth the latest procedures, methods, and applications, Copper-Mediated Cross-Coupling Reactions enables investigators to efficiently synthesize pharmaceuticals, polymers, and materials as well as create a broad array of natural products and molecular structures.
From the Back Cover
Complete, up-to-date collection of available catalytic systems and processes
Reviewing the latest advances in copper-catalyzed reactions for the formation of carbon-heteroatom and carbon-carbon bonds, this book enables readers to understand what is currently known and possible in the field, as well as where additional research is still needed. The book's comprehensive coverage offers insights into the underlying mechanisms, preparation procedures, and state-of-the-science strategies for copper-catalyzed reactions. Moreover, readers will find a complete collection of available reactions, catalytic systems and processes, as well as current and pending patents.
Starting with the Ullmann and Goldberg cross-coupling reactions, Copper-Mediated Cross-Coupling Reactions describes core applications and key advances in the field. The first two sections are dedicated to the formation of C-heteroatom bonds and C-C bonds. The third section explores applications of copper-catalyzed cross-coupling reactions, including industrial uses, and the development of environmentally friendly reactions. Among the highlights of coverage, readers will discover:
- Advances that have revolutionized pharmaceutical, polymer, and materials synthesis
- Copper-mediated procedures that have been successfully employed to assemble complex targets
- Advantages and limitations of using different catalytic systems and cross-coupling partners
- Copper-catalyzed cross-coupling reactions in natural product/bioactive molecule synthesis
- New methods for conducting copper-mediated reactions with supported catalysts that enable recyclable and reusable systems
The book features contributions from an international team of experts and pioneers in the field. Chapters are based on a thorough review and analysis of the literature as well as the authors' firsthand experience.
By setting forth the latest procedures, methods, and applications, Copper-Mediated Cross-Coupling Reactions enables investigators to efficiently synthesize pharmaceuticals, polymers, and materials as well as create a broad array of natural products and molecular structures.
About the Author
GWILHERM EVANO is a Professor at the Université Libre de Bruxelles and the Co-Director of the Laboratory of Organic Chemistry. Prof. Evano's research focuses on the development of copper-mediated transformations, chemistry of ynamides and other hetero-substituted alkynes, and total synthesis of natural products.
NICOLAS BLANCHARD is Research Director at the French National Center for Scientific Research at the University of Strasbourg. Dr. Blanchard's research interests focus on the synthesis of biologically relevant compounds using metal-mediated transformations.