Wow! eBook
Computational Medicine: Tools and Challenges 2012th Edition
Author(s): Zlatko Trajanoski
- Publisher: Springer
- Publication Date: 19 Sept. 2012
- Edition: 2012th
- Language: English
- Print length: 212 pages
- ISBN-10: 3709109469
- ISBN-13: 9783709109465
Book Description
Computational methodologies and modeling play a growing role for investigating mechanisms, and for the diagnosis and therapy of human diseases. This progress gave rise to computational medicine, an interdisciplinary field at the interface of computer science and medicine. The main focus of computational medicine lies in the development of data analysis methods and mathematical modeling as well as computational simulation techniques specifically addressing medical problems. In this book, we present a number of computational medicine topics at several scales: from molecules to cells, organs, and organisms. At the molecular level, tools for the analysis of genome variations as well as cloud computing resources for medical genetics are reviewed. Then, an analysis of gene expression data and the application to the characterization of microbial communities are highlighted. At the protein level, two types of analyses for mass spectrometry data are reviewed: labeled quantitative proteomics and lipidomics, followed by protein sequence analysis and a 3D structure and drug design chapter. Finally, three chapters on clinical applications focus on the integration of biomolecular and clinical data for cancer research, biomarker discovery, and network-based methods for computational diagnostics.
Editorial Reviews
From the Back Cover
Computational methodologies and modeling play a growing role for investigating mechanisms, and for the diagnosis and therapy of human diseases. This progress gave rise to computational medicine, an interdisciplinary field at the interface of computer science and medicine. The main focus of computational medicine lies in the development of data analysis methods and mathematical modeling as well as computational simulation techniques specifically addressing medical problems. In this book, we present a number of computational medicine topics at several scales: from molecules to cells, organs, and organisms. At the molecular level, tools for the analysis of genome variations as well as cloud computing resources for medical genetics are reviewed. Then, an analysis of gene expression data and the application to the characterization of microbial communities are highlighted. At the protein level, two types of analyses for mass spectrometry data are reviewed: labeled quantitative proteomics and lipidomics, followed by protein sequence analysis and a 3D structure and drug design chapter. Finally, three chapters on clinical applications focus on the integration of biomolecular and clinical data for cancer research, biomarker discovery, and network-based methods for computational diagnostics.
About the Author
W. Wolfgang Fleischhacker ist Facharzt für Psychiatrie und medizinische Psychotherapie. Er hat in Innsbruck studiert und wurde nach einem Forschungsaufenthalt in den USA 1983 als Professor an die Abteilung für Biologische Psychiatrie in Innsbruck berufen, seit 2008 ist er Geschäftsführender Direktor des Departments für Psychiatrie und Psychotherapie an der Medizinischen Universität Innsbruck.
Hartmann Hinterhuber ist emeritierter Professor für Psychiatrie an der Medizinischen Universität Innsbruck. Nach seinem Studium in Innsbruck und Padua absolvierte er seine Facharztausbildung in Bologna (Italien). Von 1983 bis 2008 war er Direktor der Univ.-Klinik für Psychiatrie Innsbruck. Derzeit ist er Leiter einer großen sozialpsychiatrischen Institution.
Hartmann Hinterhuber ist emeritierter Professor für Psychiatrie an der Medizinischen Universität Innsbruck. Nach seinem Studium in Innsbruck und Padua absolvierte er seine Facharztausbildung in Bologna (Italien). Von 1983 bis 2008 war er Direktor der Univ.-Klinik für Psychiatrie Innsbruck. Derzeit ist er Leiter einer großen sozialpsychiatrischen Institution.
