From the emergence of clinical sleep medicine marked by the establishment of the harbinger Stanford Sleep Disorders Clinic in the mid 1970s, offspring sleep dis- ders clinics and centers have grown exponentially with the recognition of the unmet diagnostic and treatment needs of the reservoir of patients suffering from sy- toms of what are now recognized and classi?ed as the nosology of human sleep disorders. Important in the growing armamentarium of treatment options for the sleep practitioner are both traditional and newer pharmacological agents, including over-the-counter, non-traditional, and prescription types, that are all used to treat, sometimes adjunctively, most clinically recognized sleep disorders. Although there are numerous academic treatises and reviews dealing with in- vidual treatment alternatives for the diversity of recognized sleep disorders, no one comprehensive resource, extant, has dealt with pharmacological treatment options and strategies for the major human sleep disorders associated with a panoply of symptomatic conditions. The present volume and its series of chapters individually focusing on a range of human conditions, from pediatric sleep disorders to sle- relateddisordersofindividualssufferingfromAlzheimer’sdementia,uniquelycover the wide range of human medical conditions amenable to thoughtfully sleep-related applied drug therapy. The Editors have brought together a superb group of internationally respected sleep clinicians, and researchers, that provide state-of-the-art analysis of the current basic and clinical perspective regarding the most common sleep disorders that are amenable to pharmacological treatment. In each chapter the authors outline a th- oughhistoricalbackgroundoftheparticulardisorderandreviewthebasicpre-clinicalstudies leading to current treatment options.
Editorial Reviews
From the Back Cover
The field of sleep medicine is growing rapidly, and the clinical pharmacology of sleep is gaining much attention from sleep physicians. Many new drugs are in the process of being developed and tested for their possible usefulness in the treatment of sleep disorders. The opportunity for further advancement in this field is very promising.
This volume covers the clinical and pharmacological treatment of several important sleep disorders such as insomnia, sleep apnea, narcolepsy, restless legs syndrome, and periodic limb movement syndrome. It further addresses the use of sleep medications in children, adolescents, and in the elderly. It offers a comprehensive overview of the currently available hypnotic medications and covers aspects of chronopharmacology and its implications for the pharmacology of sleep. It also reviews the basic science of sleep and sleep disorders, and thus the potential development of new pharmacological approaches.
The book will be useful for physicians, psychopharmacologists, psychiatrists, sleep disorder specialists and other healthcare professionals such as nurses, social workers and graduate medical students.
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