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Clinical Nephrotoxins: Renal Injury from Drugs and Chemicals Third Edition 2008 Edition
Author(s): Marc E. de Broe (Editor), George A. Porter (Editor), William M. Bennett (Adapter), Gilbert Deray (Adapter)
- Publisher: Springer
- Publication Date: 6 Oct. 2008
- Edition: Third Edition 2008
- Language: English
- Print length: 1004 pages
- ISBN-10: 9780387848426
- ISBN-13: 9780387848426
Book Description
Clinical Nephrotoxins: Renal Injury from Drugs and Chemicals, Third Edition is a comprehensive text on all aspects of adverse effects by drugs, chemical substances and radiation on the kidneys. The importance of the toxicity of drugs and other substances for the kidneys is increasingly recognized. The book consists of themes such as clinical relevance, renal handling and cellular mechanisms of nephrotoxicity, as well as animal and cell culture models. In addition, the volume highlights specific types of drugs, such as anti-infectious agents and anti-inflammatory, cardiovascular and anti-cancer drugs. The last section deals with prevention and focuses on urinary biomarkers, pharmacological aspects and drug dosage in renal failure. In this third and completely revised edition, several new topics were added and additional figures and tables will be included.
The book is of interest for the nephrologist, internist, general practitioner, toxicologist, pharmacologist, anesthesiologist, epidemiologist, public health official, pharmaceutical industry, and national drug safety committees, among others.
Editorial Reviews
Review
From the reviews of the third edition:
“The purpose is to provide a guide with balanced and agreed-upon information about renal injury from drugs and chemicals. … This book is a useful source of information for general clinicians, and nephrologists in particular. Intensivists, pharmacists, and investigators will also find it quite helpful. … The book is well written, easy to read, and covers essential topics in a logical sequence. … This book is particularly useful for nephrologists and I highly recommend it to medical and hospital libraries.” (Aziz Chami, Doody’s Review Services, February, 2009)
From the Back Cover
Clinical Nephrotoxins: Renal Injury from Drugs and Chemicals Third Edition 2008 Edition is a comprehensive handbook on all aspects of adverse effects by drugs and chemical substances on the kidneys. The importance of the toxicity of drugs and other substances for the kidneys is increasingly recognized.
The first, general part deals with themes as clinical relevance, renal handling, pharmacovigilance, urinary biomarkers, pharmacological, immunological and cellular aspects of nephrotoxicity, as well as animal and cell culture models. The second part includes the specific drugs; the third part gives the description of environmental and occupational nephrotoxins. The last part deals with the patient with some degree of renal failure, exposed to drugs and chemicals, the progression of renal disease, and how to adapt drug dosage.
In this third and completely revised edition, nine new chapters were added, from proton pump inhibitors to bisphosphonates, phosphate containing laxatives, oxalate, star fruit and smoking. All chapters were extended with up-to-date references.
The book is of interest for the nephrologist, internist, general practitioner, toxicologist, pharmacologist, anesthesiologist, epidemiologist, public health official, pharmaceutical industry, and national drug safety committees, among others.
