Chirality in Industry II: Developments in the Commercial Manufacture and Applications of Optically Active Compounds
Author(s): A. N. Collins (Editor), Gary Sheldrake (Editor), J. Crosby (Editor)
Publisher: Wiley
Publication Date: February 11, 1998
Language: English
Print length: 418 pages
ISBN-10: 9780471982845
ISBN-13: 9780471982845
Book Description
This second volume of Chirality in Industry contains new case histories from a wide range of contributors from industry or with strong industrial connections. While it is intended that the new volume will stand on its own, Volumes I and II taken together present an up-to-date and comprehensive picture of the technologies required to produce optically active compounds on a multi-kilogramme to high tonnage scale as well as illustrating the breadth of application of these technologies; the pharmaceuticals, agrochemicals, electronics, food, flavour and fragrance industries are all represented.
Chirality in Industry II
All new case histories
Unique industrial perspective on chiral technology
Emphasis on scale-up and process development
Comparison of biocatalysis, asymmetric synthesis and classical resolution approaches
The chiral infrastructure is now largely in place and there is no reason why large-scale production should not be possible for even moderately priced single enantiomer products. The successful industrial application of chiral chemistry depends on the integration of a range of supporting technologies and there are many examples in this volume of how widely the industrial practitioner must cast the net to achieve practical production methods. As with Volume I, this new volume is of particular interest to those professionally involved in the scale-up processes for single enantiomers. However, students and researchers involved in a more academic pursuit of optical activity will also benefit from some of the facets of large-scale thinking. An economic solution is still most likely to be a simple, elegant solution.
Editorial Reviews
From the Inside Flap
This second volume of Chirality in Industry contains new case histories from a wide range of contributors from industry or with strong industrial connections. While it is intended that the new volume will stand on its own, Volumes I and II taken together present an up-to-date and comprehensive picture of the technologies required to produce optically active compounds on a multi-kilogramme to high tonnage scale as well as illustrating the breadth of application of these technologies; the pharmaceuticals, agrochemicals, electronics, food, flavour and fragrance industries are all represented. Chirality in Industry II
All new case histories
Unique industrial perspective on chiral technology
Emphasis on scale-up and process development
Comparison of biocatalysis, asymmetric synthesis and classical resolution approaches
The ?chiral infrastructure? is now largely in place and there is no reason why large-scale production should not be possible for even moderately priced single enantiomer products. The successful industrial application of ?chiral chemistry? depends on the integration of a range of supporting technologies and there are many examples in this volume of how widely the industrial practitioner must cast the net to achieve practical production methods. As with Volume I, this new volume is of particular interest to those professionally involved in the scale-up processes for single enantiomers. However, students and researchers involved in a more academic pursuit of optical activity will also benefit from some of the facets of ?large-scale? thinking. An economic solution is still most likely to be a simple, elegant solution.
From the Back Cover
This second volume of Chirality in Industry contains new case histories from a wide range of contributors from industry or with strong industrial connections. While it is intended that the new volume will stand on its own, Volumes I and II taken together present an up-to-date and comprehensive picture of the technologies required to produce optically active compounds on a multi-kilogramme to high tonnage scale as well as illustrating the breadth of application of these technologies; the pharmaceuticals, agrochemicals, electronics, food, flavour and fragrance industries are all represented. Chirality in Industry II
All new case histories
Unique industrial perspective on chiral technology
Emphasis on scale-up and process development
Comparison of biocatalysis, asymmetric synthesis and classical resolution approaches
The ?chiral infrastructure? is now largely in place and there is no reason why large-scale production should not be possible for even moderately priced single enantiomer products. The successful industrial application of ?chiral chemistry? depends on the integration of a range of supporting technologies and there are many examples in this volume of how widely the industrial practitioner must cast the net to achieve practical production methods. As with Volume I, this new volume is of particular interest to those professionally involved in the scale-up processes for single enantiomers. However, students and researchers involved in a more academic pursuit of optical activity will also benefit from some of the facets of ?large-scale? thinking. An economic solution is still most likely to be a simple, elegant solution.
About the Author
A. N. Collins is the editor of Chirality in Industry II: Developments in the Commercial Manufacture and Applications of Optically Active Compounds, published by Wiley.
Gary Sheldrake is the editor of Chirality in Industry II: Developments in the Commercial Manufacture and Applications of Optically Active Compounds, published by Wiley.
Chirality in Industry II: Developments in the Commercial Manufacture and Applications of Optically Active Compounds
Author(s): A. N. Collins (Editor), Gary Sheldrake (Editor), J. Crosby (Editor)
Publisher: Wiley
Publication Date: March 11, 1997
Edition: 1st
Language: English
Print length: 418 pages
ISBN-10: 0471966800
ISBN-13: 9780471966807
Book Description
This second volume of Chirality in Industry contains new case histories from a wide range of contributors from industry or with strong industrial connections. While it is intended that the new volume will stand on its own, Volumes I and II taken together present an up-to-date and comprehensive picture of the technologies required to produce optically active compounds on a multi-kilogramme to high tonnage scale as well as illustrating the breadth of application of these technologies; the pharmaceuticals, agrochemicals, electronics, food, flavour and fragrance industries are all represented. Chirality in Industry II * All new case histories
* Unique industrial perspective on chiral technology
* Emphasis on scale-up and process development
* Comparison of biocatalysis, asymmetric synthesis and classical resolution approaches The chiral infrastructure is now largely in place and there is no reason why large-scale production should not be possible for even moderately priced single enantiomer products. The successful industrial application of chiral chemistry depends on the integration of a range of supporting technologies and there are many examples in this volume of how widely the industrial practitioner must cast the net to achieve practical production methods. As with Volume I, this new volume is of particular interest to those professionally involved in the scale-up processes for single enantiomers. However, students and researchers involved in a more academic pursuit of optical activity will also benefit from some of the facets of large-scale thinking. An economic solution is still most likely to be a simple, elegant solution.
Editorial Reviews
From the Publisher
Chirality describes the pharmacological, biological, and chemical consequences of molecular symmetry. This book presents an industrial rather than academic approach to chirality, allowing readers to apply it to the manufacture and commercialization of optically active products. This second volume includes important case histories and expert views from regulatory bodies. It covers antiviral nucleosides, chiral liquid crystals, membrane technology for racemate separation and all aspects of the scale-up and manufacture of optically active intermediates and products.
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