The Behavioral Neurology of White Matter

The Behavioral Neurology of White Matter book cover

The Behavioral Neurology of White Matter

Author(s): Christopher M. Filley (Author)

  • Publisher: OUP USA
  • Publication Date: 18 Oct. 2001
  • Language: English
  • Print length: 298 pages
  • ISBN-10: 019513561X
  • ISBN-13: 9780195135619

Book Description

This unique book examined the role of the brain’s white matter in the organization of human mental function. The white matter is discussed as an important complement to cortical and subcortical gray matter in the distributed neural networks that subserve all aspects of cognition and emotion. The book is founded on the study of patients with white matter disorders, and considers white matter dementia and other neobehavioral syndromes in developing a behavioral neurology of white matter.

Editorial Reviews

Review

Clinicians and neurobiologists from many disciplines will find this to be a useful volume. The description of the diseases themselves is a worthwhile contribution, and creating the context for these disorders in an understanding of the neurobiology of white matter provides a unique new perspective on old diseases. Those who make themselves students of Dr Filley’s extensive knowledge of white matter and white matter disorders by reading this book will find themselves richly rewarded for their efforts. (Jeffrey L Cummings, M.D., Director, UCLA Alzheimer’s Disease Center, The Augustus S. Rose Professor of Neurology, and Professor of Psychiatry and Biobehavioral Sciences, UCLA School of Medicine)

In this soon-to-be landmark textbook, Dr Filley provides an integrative framework for understanding the unique role of white matter in influencing the distributed neural networks that govern higher mental functions. The Behavioral Neurology of White Matter is essential reading for all who seek knowledge of how the brain impacts behaviour. (Stephen M Rao, Ph.D, Professor of Neurology, Medical College of Wisconsin)

Not a week goes by in my clinical practice without having to address the nature of white matter abnormalities seen on a patient’s MRI scan . . . Dr Filley’s book represents the most comprehensive state-of-the-art approach to this emerging and increasingly important topic. I will keep it by my desk for regular consultation. (Bruce H Price, M.D., Chief, Department of Neurology, McLean Hospital and Assistant Professor of Neurology, Harvard Medical School)

Dr Filley has marshaled an impressive amount of evidence – clinical, experimental, and radiological – to compel a realization that, in some instances, mental functioning and behaviour may depend as much on the integrity of cerebral white matter as on gray. This important work will help neurologists in particular to develop familiarity with clinical white matter disorders that cause higher cerebral dysfunction (Stuart A Schneck, M.D., Professor Emeritus of Neurology, University of Colorado School of Medicine)

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