Wow! eBook
Autophagy, Apoptosis and Ferroptosis in Oncology: Cell Death and Cancer
Author(s): Kiavash Hushmandi (Editor), Alan Prem Kumar
- Publisher: World Scientific Publishing Co Pte Ltd
- Publication Date: 28 April 2025
- Language: English
- Print length: 980 pages
- ISBN-10: 9811299315
- ISBN-13: 9789811299315
Book Description
This book aims to provide a comprehensive exploration of three critical processes involved in cell death and survival, each playing a unique role in cancer development, progression, and treatment. Autophagy, apoptosis, and ferroptosis are distinct yet interconnected pathways that regulate cellular homeostasis and response to stress. In the context of oncology, these processes are of paramount importance. Cancer cells often manipulate autophagy and apoptosis to their advantage, evading death and promoting survival even in the face of therapeutic interventions.
Understanding these mechanisms provides valuable insights into how cancer can be effectively targeted and treated. Furthermore, the emerging role of ferroptosis adds an exciting dimension to the ongoing quest for innovative cancer therapies. This book is structured to offer a detailed examination of each process, beginning with their fundamental biological mechanisms, followed by their implications in cancer biology.
The chapters are designed to guide the reader through the intricate interplay between autophagy, apoptosis, and ferroptosis, highlighting recent discoveries, ongoing research, and potential therapeutic applications.
Editorial Reviews
About the Author
Dr Alan Prem Kumar is Assistant Professor at the Department of Pharmacology, National University of Singapore Medicine and Assistant Dean for Graduate Studies and Director of the Office of Postdoctoral Affairs. Additionally, Dr Kumar also serves as the Deputy Director for External Collaborations & Academic Outreach.
In recognition of his dedication to student supervision, Dr Kumar received the Yong Loo Lin School of Medicine, NUS Graduate Mentor of the Year Award twice, in 2017 and 2021. His contributions to translational research have been acknowledged with four consecutive recognitions as a World’s Top 1% Highly Cited Researcher™ by Clarivate, spanning from 2020 to 2023. Furthermore, Dr Kumar is also recognized as one of the Top 2% of Scientists Worldwide in the field of Biology and Biochemistry by a Stanford University study in 2022 and 2023.
Dr Kumar serves on the Scientific Advisory Boards for GenoMed, Inc. (USA), focusing on Oncology Markers; Sansad Mobile Swasthya Seva Healthcare Program, Parliament of India (India), addressing Breast Cancer Awareness and Screening; The Sparks Foundation (Singapore), dedicated to Education; and AUM Biosciences (Singapore), specializing in Oncology Drug Acquisitions.
Dr Kiavash Hushmandi is an Assistant Professor at Baqiyatallah University of Medical Sciences. After receiving the doctor of veterinary medicine degree, he joined the University of Tehran as PhD student in the field of Molecular Epidemiology. His major interests include cancer therapy, nanoparticles, cell death mechanism and application of natural products in cancer therapy.
