Annotating New Genes: From In Silico Screening to Validations by Experiments: From in Silico Screening to Experimental Validation annotated edition

In Annotating new genes the author considers his team’s approach as applied to evolutionary-conserved, heart-enriched genes with unknown functions. All the above mentioned methods have been validated by students working in the field of bioinformatics and developmental biology to provide a step-by-step methodology to obtain highly publishable data as well as knowledge creation that will aid the development of products which can be used in the field of regenerative medicine.

Key Features: focuses not only on screening but also on biological validations; provides details of databases and software (web interface) products for biologists with minimal computation skills; offers a step-by-step outline of the procedure involved; includes a case-study of C-It for use in in silico screening.

Contents: Databases and software to make your research life easier; How to program like a bioinformatician? Case study: C-It, knowledge database for screening evolutionarily conserved, tissue-enriched, uncharacterized genes; Experimental validation: concepts and practice; Further application: adult stem cells and tissue regenerations; Conclusion.