Wow! eBook
Allosteric Receptor Modulation in Drug Targeting
Author(s): Norman G. Bowery
- Publisher: CRC Press
- Publication Date: June 19, 2006
- Edition: 1st
- Language: English
- Print length: 376 pages
- ISBN-10: 0824727916
- ISBN-13: 9780824727918
Book Description
Offering a wide array of illustrations and tables in every chapter, this book extensively covers the principles of allosterism in reference to drug action and progresses to a detailed examination of individual ionotropic and G-protein coupled receptor systems-helping those new to the subject understand the importance of allosterism and providing those already working in the field with specific reference information. This title provides in-depth chapters on basic principles of allosterism and its significance at GABAA, 5HT3, nicotinic, and GABAB receptors, ionotropic and metabotropic receptors for glutamate, muscarinic receptors and alpha 2 adrenoceptors to provide a firm foundation to the subject.
Editorial Reviews
Review
“…This book provides valuable theoretical and practical information on receptor allosterism and its potential importance in the design and development of novel therapeutics. It is a unique offering in stressing the importance of allosterism in drug discovery. This makes it a particularly important contribution for industrial and academic scientists and clinicians with an interest in new approaches for designing safer, more selective, and efficacious drugs.” -Doody’s Review Services
About the Author
Norman G. Bowery
