Advances in Circular RNAs: The Basis and Disease Relevance

This book provides a comprehensive overview of circular RNAs (circRNAs), a novel class of non-coding RNAs with diverse regulatory roles and clinical relevance. Covering recent advances in circRNA biogenesis, molecular mechanisms, computational tools, and disease associations, it offers a structured and up-to-date resource. Readers will gain insights into how circRNAs influence gene regulation, participate in human diseases, and serve as potential biomarkers and therapeutic targets. This book is ideal for researchers, clinicians, and students interested in RNA biology, bioinformatics, and precision medicine.

Dr. Junjie Xiao is the executive dean of the School of Life Science, Shanghai University, China. In addition, he is the director of the Key Laboratory of Biomedical Materials and Technology for Organ Regeneration of the Ministry of Education, the director of the Shanghai Organ Regeneration Engineering Technology Research Centre, and the head of the Cardiovascular Research Institute of Shanghai University. He is an Associate Editor of Journal of Molecular and Cellular Cardiology and Journal of Cardiovascular Translational Research, and is on the editorial boards of several other notable journals. He has authored or co-authored in journals such as Cell Metabolism, Circulation, Circulation Research, and Nature Communications, etc. His research focuses on heart failure intervention and risk prediction, with a particular emphasis on exercise-induced cardiac regeneration and the identification of novel therapeutic targets. He is also interested in epigenetic and metabolic regulations of cardiac function upon exercise and under pathological conditions.