Advanced Wound Repair Therapies

Key Features: provides readers with up-to-date information on current and emerging biomaterials and advanced therapies concerned with healing surgical and chronic wounds; chapters include the role of micro-organisms and biofilms in dysfunctional wound healing, tissue-biomaterial interaction and electrical stimulation for wound healing; covers biologically-derived and cell-based therapies for chronic wounds, including engineered tissues, biologically-derived scaffolds and stem cell therapies for wound repair.

Contents: Part 1 Introduction to chronic wounds: Dysfunctional wound healing in chronic wounds; The role of micro-organisms and biofilms in dysfunctional wound healing; Scarring and scarless wound healing; The discovery and development of new therapeutic treatments for the improvement of scarring; Monitoring chronic wounds and determining treatment. Part 2 Biomaterial therapies for chronic wounds: Functional requirements of wound repair biomaterials; Tissue-biomaterial interaction; Polymeric materials for chronic wound and burn dressings; Dry wound healing concept using spray-on dressing for chronic wounds; Assessing the effectiveness of antimicrobial wound dressings in vitro; Adhesives and interfacial phenomena in wound healing; Wound healing studies and interfacial phenomena: Use and relevance of the corneal model; Sulphonated biomaterials as glycosaminoglycan mimics in wound healing. Part 3 Molecular therapies for chronic wounds: Drug delivery dressings; Molecular and gene therapies for wound repair; Antimicrobial dressings; Avotermin: emerging evidence of efficacy for the improvement of scarring. Part 4 Biologically-derived and cell-based therapies for chronic wounds: Engineered tissues for wound repair; Commercialisation of engineered tissue products; Biologically derived scaffolds; Stem cell therapies for wound repair. Part 5 Physical stimulation therapies for chronic wounds: Electrical stimulation for wound healing; Negative pressure wound therapy; Debridement methods of non-viable tissue in wounds.