Putting Pharmacokinetics and Pharmacodynamics to Work in Drug Discovery: A Practical Guide for Pharmaceutical Scientists
by: Emile P. Chen (Author)
Publisher: Wiley
Edition: 1st
Publication Date: 2025-05-09
Language: English
Print Length: 560 pages
ISBN-10: 1119650208
ISBN-13: 9781119650201
Book Description
Develop drugs with a greater understanding of their bodily impactPharmaceutical scientists in the fields of pharmacokinetics and pharmacodynamics study how drugs behave in the body and how they reach their site of action to exert their intended pharmacological activities. Drug discovery stands to benefit enormously from the timely application of pharmacokinetics and pharmacodynamics in order to make informed decisions and solve practical problems. Putting Pharmacokinetics and Pharmacodynamics to Work in Drug Discovery bridge between scientific concepts and practical industrial practice by bringing these principles to bear on every stage of the drug discovery process. Beginning with target identification and moving through each subsequent decision point including high throughput screening, hit-to-lead, lead optimization and candidate selection. The book offers a comprehensive guide to minimizing attrition, reducing costs, and more. The result is an invaluable tool in developing smarter and more effective drug discovery processes. Putting Pharmacokinetics and Pharmacodynamics to Work in Drug Discovery readers will also find: A work designed to make scientific principles accessible to pharmaceutical scientists in diverse areas, not just pharmacokinetists or DMPK scientistsIndustrial examples, both positive and negative, showing pharmacokinetic and pharmacodynamic principles at workInteractive exercises at the end of each section to encourage holistic and integrated thinkingPutting Pharmacokinetics and Pharmacodynamics to Work in Drug Discovery is ideal for any researchers or professionals involved in drug discovery and development, including medicinal chemists, biopharmaceutics scientists, clinicians, project leaders, and many others.
Editorial Reviews
Develop drugs with a greater understanding of their bodily impactPharmaceutical scientists in the fields of pharmacokinetics and pharmacodynamics study how drugs behave in the body and how they reach their site of action to exert their intended pharmacological activities. Drug discovery stands to benefit enormously from the timely application of pharmacokinetics and pharmacodynamics in order to make informed decisions and solve practical problems. Putting Pharmacokinetics and Pharmacodynamics to Work in Drug Discovery bridge between scientific concepts and practical industrial practice by bringing these principles to bear on every stage of the drug discovery process. Beginning with target identification and moving through each subsequent decision point including high throughput screening, hit-to-lead, lead optimization and candidate selection. The book offers a comprehensive guide to minimizing attrition, reducing costs, and more. The result is an invaluable tool in developing smarter and more effective drug discovery processes. Putting Pharmacokinetics and Pharmacodynamics to Work in Drug Discovery readers will also find: A work designed to make scientific principles accessible to pharmaceutical scientists in diverse areas, not just pharmacokinetists or DMPK scientistsIndustrial examples, both positive and negative, showing pharmacokinetic and pharmacodynamic principles at workInteractive exercises at the end of each section to encourage holistic and integrated thinkingPutting Pharmacokinetics and Pharmacodynamics to Work in Drug Discovery is ideal for any researchers or professionals involved in drug discovery and development, including medicinal chemists, biopharmaceutics scientists, clinicians, project leaders, and many others.